[Giant optic disk melanocytoma complicated with massive intraocular seeding].
نویسندگان
چکیده
CASE REPORT A 33 year-old female with a large, unilateral, dark tumour of the optic disk with a presumed diagnosis of melanocytoma. After a follow-up of nineteen years, the tumour produced massive intraocular seeding with cataract, secondary glaucoma (pigmentary, melanocytomalytic, inflammatory and pupillary seclusion glaucoma) and amaurosis. The eye is enucleated and the pathological examination confirmed the diagnosis. DISCUSSION Optic disk melanocytoma is a benign stationary tumour. However, sometimes that are to complications, including visual loss. Our case confirms that vitreous seeding is due to tumour necrosis with dissemination of tumoral debris and melanin, which are phagocytized by macrophages and produce an inflammatory reaction, trabecular plugging and ocular hypertension.
منابع مشابه
Clinical Findings and Genetic Expression Profiling of Three Pigmented Lesions of the Optic Nerve
Background. Optic disk melanocytoma is a primary tumor of the optic disk that represents a clinical diagnostic challenge due to its similarities with melanoma. Purpose. The authors present three cases in which genetic expression profiling was used to identify tumor prognosis of optic disk melanocytoma. Case Series. In two cases fine-needle aspiration biopsy was performed to obtain tissue throug...
متن کاملBevacizumab for the treatment of a complicated posterior melanocytoma
PURPOSE To present a case of a complicated posterior melanocytoma that was successfully treated with intravitreal bevacizumab. CASE REPORT A 50-year-old Caucasian man was referred with sudden-onset metamorphopsia and decreased vision in his right eye over the course of the last 2 months. His best-corrected visual acuity was 20/80 and poorer than Jaeger 14 in the right eye, and 20/20 and Jaege...
متن کاملOcular adverse effects associated with cyclooxygenase-2 inhibitors.
1. Zimmerman LE, Garron LK. Melanocytoma of the optic disc. Int Ophthalmol Clin. 1962;2: 431-440. 2. Joffe L, Shields JA, Osher RH, Gass JD. Clinical and follow-up studies of melanocytomas of the optic disc. Ophthalmology. 1979;86:10671083. 3. Spencer WH. XXXIV Edward Jackson Memorial Lecture: drusen of the optic disc and aberrant axoplasmic transport. Ophthalmology. 1978;85:21-38. 4. Osher RH,...
متن کاملClinicopathological findings in a growing optic nerve melanocytoma.
We present an unusual case of a melanocytoma of the optic disc that showed documented progressive growth over a period of six years. It reached the largest size of any reported optic nerve melanocytoma and the eye was enucleated because of the possibility of malignant degeneration. Optic nerve melanocytomas are locally invasive but are not known to undergo transformation into malignant melanoma...
متن کاملCentral retinal vascular obstruction secondary to melanocytoma of the optic disc.
A 35-year-old black man developed abrupt visual loss in his left eye. Ophthalmic examination revealed a deeply pigmented mass obscuring the optic disc, hemorrhagic retinopathy, and signs of central retinal vascular obstruction. Fluorescein angiography disclosed sluggish filling of the retinal blood vessels; ultrasonography disclosed an acoustically solid mass in the optic nerve head. Cytopathol...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Archivos de la Sociedad Espanola de Oftalmologia
دوره 86 5 شماره
صفحات -
تاریخ انتشار 2011